The ADAMTS5 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ADAMTS5, and Aggrecanase-2. This antibody recognizes Human, Mouse, and Rat antigen. The ADAMTS5 Antibody has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage